Medicine in Ancient Egypt Essays

Medicine in Ancient Egypt Essays Medicine in Ancient Egypt Paper Medicine in Ancient Egypt Paper Essay Topic: Burial Rites Love Medicine People sometimes say that the ancient Egyptian civilization endured without much change for more than three thousand years. This is only partially true because, in fact, Egyptian ways of life, philosophy, religion, language, and art changed considerably over time. However, the ancient Egyptian culture retained its identity and general character to a remarkable degree over the course of its history: a situation due in part to Egypt’s favorable and secure location. Essentially a river oasis, the country was bordered by deserts to the west and east, by the Mediterranean Sea to the north, and by the first cataract of the Nile at Aswan in the south. Situated in the northeastern corner of Africa, Egypt was a center for trade routes to and from western Asia, the Mediterranean, and central Africa. Ancient Egyptian medicine is the medicine that was commonly practiced in Ancient Egypt from circa 3300BC until Persian invasion of 525 BC. The medicine was highly advanced for the time and included surgery, setting of bones and extensive set of Pharmacopoeia. Remedies were sometimes characterized by magical incantations and dubious ingredients, often had a rational basis. Medical texts specified specific steps of examination, diagnosis, prognosis and treatments that were rational and appropriate. The practices of Egyptian physicians ranged from embalming, to faith healing to surgery, and autopsy. There was no separation of Physician, Priest and Magician in Egypt. Healing was an art that was addressed on many levels during ancient Egyptian period Modern medicine owes much to the Ancient Egyptians. Historians divide the history of Ancient Egypt ancient Egypt into: Prehistory (up to ca. 3100 B. C. ), the Archaic Period (ca. 3100- 2650 B. C. ) the Old Kingdom (ca. 2650-2150 B. C. ), the Middle Kingdom (ca. 2040-1640 B. C. ), the New Kingdom (ca. 1550-1070 B. C. ), the Late Period (ca. 712-332 B. C. ), and the Ptolemaic (Hellenistic) and Roman Periods (332 B. C. -A. D. 395). The main sources of information about ancient Egyptian medicine were writings from antiquity until 19th century as in Odyssey (800B. C), observations recorded by Greek historian Herodotus (440BC), writings of Pliny the Elder. The father of modern medicine Hippocrates (ca 460BC-370BC), Herophilos (ca335-280 BC) Erasistratus (ca 310 BC-250BC, who founded a school of anatomy) and Galen studied at the temple of Amenhotep and acknoledged the contribution of ancient Egyptian medicine to Greek medicine. Much of what we now know of Egyptian medicine and the work of the physicians come from a variety of medical documents written by physician-priests. These documents, known as papyrus are the first known records of medical practice. The various papyrus documents that have been recovered and translated show us that the Egyptians had developed an understanding of medicine. The evidence provided by these early medical training manuals is quite remarkable. They show quite clearly that the Egyptians had identified and developed cures for a wide range of diseases, many of which cures are still in use today. Such was the extent of Egyptian knowledge that there are records of over 800 medical procedures and remedies making use of over 600 drugs and a vast array of surgical tools. A few papyri have survived, from which we can learn about Egyptian medicine: The Edwin Smith Papyrus describing surgical diagnosis and treatments: opens with eight texts concerning head wounds, followed by nineteen treatments of wounds to the face, six descriptions of how to deal with injuries to throat and neck, five dealing with collar-bones and Ancient Egypt arms, and seven with chest complaints. Some important notions concerning the nervous system originated with the Egyptians, a word for brain is used here for the first time in any written language: â€Å"the membrane enveloping his brain, so that it breaks open his fluid in the interior of his head† (The Edwin Smith papyrus, case6). Acting conservatively, they knew how to treat injuries to the brain without killing the patient, but on the whole their understanding of the brain and its functions was superficial: they considered thinking to be a function of the heart. Their dissection of bodies during mummification seems not to have added greatly to their knowledge of the inner workings of the human body, possibly because mummifiers and physicians did not move in the same circles. The Ebers Papyrus on ophthalmology, diseases of the digestive system, the head, the skin and specific maladies like aAa, which some think may have been a precursor of AIDS and others consider to have been a disease of the urinary tract. Kahun Gynecological Papyrus, the Berlin Medical papyrus, the London Medical Papyrus, the Hearst medical papyrus and the Demotic magical Papyrus of London and Leiden: contains a number of spells for treating physical ailments, also give extensive information about the medicine during ancient Egypt. The cause of diseases, Anatomy, Physiology and practices The human body was believed to be born in a healthy state, and could not fall ill or die except through the influence of a foreign agent. In case of wounds or intestinal worms, that agent was visible and the treatment prescribed was hence rational. As they were not aware of microbiology, internal diseases were thought to be due to an occult force attributed to evil gods, a divine punishment or magical procedures. The physician was obliged to neutralize this evil Ancient Egypt before turning into actual treatment. The use of Autopsy came through the extensive embalming practices of the Egyptians, as it was not unlikely for an embalmer to examine the body for a cause of the illness which killed it. The use of surgery also evolved from a knowledge of the basic anatomy and embalming practices of the Egyptians. From such careful observations made by the early medical practitioners of Egypt, healing practices began to center upon both the religious rituals and the lives of the ancient Egyptians. The prescription for a healthy life, which was always given by a member of the priestly caste, meant that an individual undertook the stringent and regular purification rituals, and maintained their dietary restrictions against raw fish and other animals considered unclean to eat. In addition to a purified lifestyle, it was not uncommon for the Egyptians to undergo dream analysis to find a cure or cause for illness, as well as to ask for a priest to aid them with magic, this example obviously portrays that religious magical rites and purificatory rites were intertwined in the healing process as well as in creating a proper lifestyle. The practice of medicine was fairly advanced in Ancient Egypt, with Egyptian physicians having a wide and excellent reputation. Sovereigns from foreign lands have frequently appealed to pharaohs to send them their physicians. A wall painting in a Thebean grave of the 18th dynasty (1400 BC) depicts â€Å"Nebamun†, scribe and physician of the king, receiving a Syrian prince paying him for his services in gifts. According to Herodotus, King Cyrus of Persia has requested Amasis (Ahmose II of the 26th dynasty, 560 BC) to send him the most skilful of all the Egyptian eye-doctors. Egyptian physicians recognized the heart as the source of blood vessels. They were aware that the blood vessels were hollow, having a mouth which opens to absorb medications, Ancient Egypt eliminate waste elements, distribute air and body secretions and excretions, in confusion between blood vessels and other passages, as ureters. The physiology of blood circulation was demonstrated in the Edwin Smith Papyrus, together with its relation to the heart, as well as awareness of the importance of the pulse. They also knew that blood supply runs from the heart to all organs of the body. â€Å"There are vessels in him for every part of the body†. â€Å"It speaks forth in the vessels of every body part† (Edwin Smith Papyrus) However, their inability to distinguish between blood vessels, nerves, tendons and channels has limited their full understanding of the physiology of circulation. The diseases: The common cold plagued the ancient Egyptians as it still does us today, and their remedy, the milk of a mother who has given birth to a boy, was probably as effective as anything we have got today. Insect, especially scorpion bites or snake bites, both very frequent in Egypt, were treated by magicians, as there appears to have been no specific balm or ointment used, and as we have records of many spells, written on papyri and magical charms devoted to these two occurrences. Bilharziasis (schistosomiasis) a common disease in a country flooded for months every year a common cause of anemia, female infertility, a debilitating loss of resistance to other diseases and subsequent death. The Ebers Papyrus addresses some of the symptoms of the disease and in two columns discusses treatment and prevention of bleeding in the urinal tract (haematuria). The Hearst Papyrus cites antimony disulfide as a remedy. Insect borne diseases like malaria and trachoma were endemic; plagues spread along the trade routes and a number of yadet renpet epidemics reported in Egyptian documents are thought by some to Ancient Egypt have been outbreaks of bubonic plague. Smallpox, measles, and cholera were easily propagated in the relatively densely populated Nile valley, where practically the whole population lived within a narrow strip of land. Silicosis of the lungs, the result of breathing in airborne sand particles, was a frequent cause of death, as was pneumonia. The various kinds of malignant tumors were almost as frequent then as they are nowadays in comparable age and gender groups. Eye infections are a common complaint in Africa. In ancient Egypt they were at least in part prevented by the application of bactericidal eye paint. The ingredients of some of the remedies may not have been as difficult to come by in a civilization where the brain was removed in little bits from the skull during mummification as it would be in a modern western country. ‘Prescription for the eye, to be used for all diseases which occur in this organ: Human brain, divide into its two halves, mix one half with honey, smear on the eye in the evening, dry the other half, mash, sift, smear on the eye in the morning’(Ebers Papyrus). Open wounds were often treated with honey. But sometimes lockjaw set in. When a tetanus infection was recognized, physicians knew they were powerless against this affliction. Dietary Deficiencies: A restricted diet caused or aggravated a number of ailments; some with fatal outcome . There were times when malnutrition was widespread. Growth of the population was therefore often stunted. Because of vitamin and other deficiencies, dental abrasion, and bad mouth hygiene, caries and abscesses were the lot of many. Herbal medicines: Herbs played a major part in Egyptian medicine. The plant medicines mentioned in the Ebers papyrus include opium, cannabis, myrrh, frankincense, fennel, cassia, Ancient Egypt senna, thyme, henna, juniper, aloe, linseed and castor oil. Cloves of garlic have been found in Egyptian burial sites. Egyptians thought garlic and onions aided endurance, and consumed large quantities of them. Raw garlic was routinely given to asthmatics and to those suffering with bronchial-pulmonary complaints. Coriander (C. Sativum) was considered to have cooling, stimulant, carminative and digestive properties. Cumin (Cumin cyminum) is an umbelliferous herb indigenous to Egypt. The seeds were considered to be a stimulant and effective against flatulence. Cumin powder mixed with some wheat flour as a binder and a little water was applied to relieve the pain of any aching or arthritic joints. Tape worms, the snakes in the belly, were dealt with by an infusion of pomegranate root in water, which was strained and drunk. Ulcers were treated with yeast, as were stomach ailments. Some of the medicines were made from plant materials imported from abroad. Mandrake, introduced from Canaan and grown locally since the New Kingdom, was thought to be an aphrodisiac and, mixed with alcohol, induced unconsciousness. Oil of fir, an antiseptic, originated in the Levant. The Persian henna was grown in Egypt since the Middle Kingdom, and if identical with henu mentioned in the Ebers Papyrus was used against hair loss. They treated catarrh with aloe which came from eastern Africa. Frankincense, containing tetrahydrocannabinol and used like hashish as pain killer, was imported from Punt. Animal products and minerals were used too. Honey and grease formed part of many wound treatments, mothers milk was occasionally given against viral diseases like the common cold, fresh meat laid on open wounds and sprains, and animal dung was thought to be effective at times. Malachite used as an eye-liner also had therapeutic value. In a country where eye Ancient Egypt infections were endemic, the effects of its germicidal qualities were appreciated even if the reasons for its effectiveness were not understood. Pregnancy and childbirth: Fertility was important to the Egyptians and the Kahun Gynecological Papyrus includes a number of tests for it. At the same time there seems to have existed the need for planning pregnancies. Silphium grown in Cyrene was famous for many medical qualities, including its contraceptive properties. They also devised the first known pregnancy test: Means for knowing if a woman will give birth or will not give birth: (Put) some barley and some wheat (into two bags of cloth) which the woman will moisten with her urine every day, equally barley and grain in the two bags. If both the barley and the wheat sprout she will give birth. If (only) the barley germinates it will be a boy, if it is the wheat which alone germinates it will be a girl. If neither germinates she will not give birth (Berlin papyrus 3. 038) The Ebers papyrus mentions two remedies which cause all to come out which is in the stomach of a woman, possibly referring to inducing a miscarriage. Birth itself was dangerous both to the mother and the baby. Infant mortality was high, probably around 30 percent, and complications and child bed fever killed many women. Surgery: At Saqqara there is the tomb of Ankh-Mahor, known as The Tomb of the Physician. In one of the wall pictures two men are having their extremities treated variously explained as manicure, massage or surgery. Another picture shows the performance of a circumcision of adolescents (the only instance of a depiction of this procedure) with the hieroglyphs saying The ointment is used to make it acceptable, which has been interpreted as meaning that a local Ancient Egypt anesthetic was being used, though this reading is, as happens often in such inscriptions, doubtful. Poppies are occasionally mentioned in Egyptian medical literature and the physicians had a pretty good idea of their properties. Boys destined for priesthood were circumcised as part of the initial ritual cleansing, which also included the shaving of the whole body. The practice of circumcision became more universal during the Late Period, perhaps as part of a rite of passage. Prostheses and cosmetics: Prostheses were generally of a cosmetic character, such as an artificial toe made of cartonnage at the British Museum, or added as a preparation for afterlife such as a forearm on a mummy in Arlington Museum (England) and an artificial penis and feet on another mummy in the Manchester Museum . Wooden big toe prosthesis has also been found in a fifty to sixty year old woman, after her big toe had been amputated, possibly because of gangrene. A glass eye with a white eyeball and a black pupil, but lacking an iris, was probably inserted into the empty eye socket of a mummy rather than used by a living person. Physicians performed other cosmetic tasks as well. Apart from prescribing lotions, salves and unguents for skin care, they also produced remedies against the loss of hair and graying, which was combated by an ointment made with blood from the horn of a black bull. Hair loss was hoped to be stopped by a mixture of honey and fats from crocodiles, lions, hippos, cats, snakes, and ibex. Dentistry: As their diet included much abrasive material (sand and small stone particles from grinding the corn) the teeth of the ancient Egyptians were generally in a very poor state. Caries and the destruction of the enamel caused the loss of teeth at an early age and often killed as well. Caries were sometimes treated by fillings made of resin and chrysocolla, a greenish mineral containing copper. Swollen gums were treated with a concoction of cumin, incense and Ancient Egypt onion. Opium might be given against severe pain. At times holes were drilled into the jawbone in order to drain abscesses. But extraction of teeth, which might have saved the lives of many a patient, was rarely if ever practiced. The profession of dental physician seems to have existed since the early third millennium: Hesi-re is the first known Doctor of the Tooth. Physicians: The ancient Egyptian word for doctor is swnw. Hesi-re was the earliest recorded physician and the lady Peseshet (2400BC) may be the first recorded female doctor. Most famous of the Egyptian physicians is Imhotep, who is also renowned for his role as a Pyramid designer. Imhotep used a variety of methods to heal patients but based much of their practice upon religious belief. It was common for different priests to act as physicians for different parts of the body, in much the same way that doctors specialize now, as they believed that different gods governed different sectors of the human body. Medical institutions were known to have established in ancient Egypt since as early as the 1st dynasty (3100- 2600BC) and by 19th dynasty (1550-1070 BC) their employees enjoyed benefits like medical insurance, pensions and sick leave and they worked 8hours a day. Magic and religion: Magic and religion were part of everyday life in ancient Egypt and Gods and demons were thought to be responsible for many illness. So often the treatments involved a supernatural element: the first attempt was an appeal to a deity. Priests and magicians were called on to treat the disease instead or in addition to a physician. Physicians often used incantations and magical ingredients as a part of the treatment and many medicines apparently lacked active ingredients. The wider spread use belief in magic and religion may have contributed to a powerful placebo effect. The impact of the magic is seen in the selection of remedies or ingredients for them. Depiction of a medical kit: 1) knives, 2) drill, 3) saw, 4) forceps or pincers, 5) censer, 6) hooks, 70 bags tied with string,(8, 10) beaked vessel, 11) vase with burning incense, 12) Horus eyes, 13) scales, 14) pot with flowers of Upper and Lowed Egypt, 15) pot on pedestal, 16) graduated cubit or papyrus scroll with out side knot ( or a case holding reed scalpels), 17) shears, 18) spoons. Conclusion: The people of Ancient Egypt made several major medical discoveries and began treating diseases in a physical manner alongside older spiritual cures. Though much of the advancement in medical knowledge and practice was a side effect of religious ceremonies the effect on public health and knowledge of the human body was tremendous. Fuelled by a desire to enter the afterlife Egyptian knowledge of the workings of the body encompassed new areas of medicine ranging from a basic understanding of anatomy to the introduction of some surgical skills. Ancient Egypt References: 1. Allen, Thomas George ;1936, Egyptian Stelae, Field Museum of Natural History: Anthropological Series; Vol. XXIV, No. 1, Chicago 2. Breasted, J. H. (1906) Ancient Records of Egypt 3. Breasted, J. H. (1930) The Edwin Smith Surgical Papyrus (University of Chicago Press: University of Chicago,) 4. Brian Brown (ed. ) (1923); The Wisdom of the Egyptians. New York: Brentanos 5. Buikstra, J. E. ; Baker, B. J. ; Cook, D. C. (1993) What Disease Plagues the Ancient Egyptians? A Century of Controversy Considered, In Biological Anthropology and the Study of Ancient Egypt (eds. ) W,V. Davies and R. Walter (British Museum Press: London,) 6. Hurry, Jamieson, B. (1926) ; Imhotep, Oxford University Press 7. Nunn, J. F. (1996) Ancient Egyptian Medicine (University of Oklahoma Press: Norman,) 8. Sandison, A. T. ( 1980) Diseases in Ancient Egypt, in Mummies, Disease, and Ancient Cultures (eds. ) Aiden and Eve Cockburn (Cambridge University Press: Cambridge, 9. Sameh M. Arab, MDMEDICINE IN ANCIENT EGYPT 10. Scarre, Christopher; Fagan, M. Brian; 1997, Ancient Civilizations, Longman 11. mic. ki. se/Egypt. html 12. http://nefertiti. iwebland. com/timelines/topics/medicine. htm

Conflict Resolution - Mediation 2 Essay Example | Topics and Well Written Essays - 2500 words

Conflict Resolution - Mediation 2 - Essay Example Unlike arbitrators, the mediator has no legal authority of imposing any decision rules but relies on persuasion in order to reach an agreement to the dispute. The process involves confidential meetings with the participants where the mediator has no liberty to reveal what the participant said during the meeting without the express consent of the participant. The mediation process involves key steps which include the opening statement at the meetings, education phase, options (alternatives) generation phase, negotiation phase and closing phase (Billikopf 1). The opening statement involves setting the rules of engagement like confidentiality requirements and ground rules of approaching the negotiation phase. The education phase of the mediation phase entails setting the perspectives of the dispute, the key needs of each disputant and feelings of each party to the dispute. At this stage, the disputants are required to relive themselves of any negative feelings towards each other and con fidently state their desired outcome towards the dispute. The alternatives seeking stage involves brainstorming and searching for the viable alternatives of ending the dispute. The negotiation parties explore the alternatives of ending the dispute at the negotiation stage while the final stage includes closing the dispute with the most viable and mutually agreed solution of settlement (Billikopf 2). Transformative dispute mediation style involves an opportunity for moral growth and empowerment of the parties to the dispute. The mediator will encourage the debate to the conflict and direct the process while adhering to the ground rules set by the parties. Problem solving mediation sees the conflict as a short term situation that needs a solution whereby the mediator acts as an expert in finding the solutions to the settlement. The mediator can adopt a party controlled approach whereby discussions include broad questions and allowing emotions or an evaluative approach whereby emotions are limited and have authority to direct the discussions. Some principles to mediation include openness, balanced approach, resourcefulness, inspiration and tactfulness in approaching the mediation process. The mediator should remain impartial and neutral during the mediation process while disclosing any potential instances that may cause conflicts of interest. The mediator should build confidence to the process by showing his confidence and trust which is demonstrated by his or her ability to smile, listen, remain tactful and build cordial relationships with all the disputants. The mediator should undertake the responsibility of ensuring no potential instances that contribute to conflict of interest which can jeopardize his impartiality and neutrality to the mediation process. Emotions such as anger, sadness and shame should be avoided during the mediation process since they may result to defensiveness or criticism during the mediation process. During a party-mediated process, the mediator should conduct the mediation process in a manner which ensures competence and mutual respect to all the disputants. Some levels of resolution which are critical include the end to behavioral fighting, settlement of conflict issues, eliminating the emotional tensions and reconciliation of the outstanding disputes between the disputants. Party directed mediation is mainly useful when poor communication, and personality conflicts exist which threaten the ongoing interpersonal relations. The purpose of

MGMT 436 U5 DB Research Paper Example | Topics and Well Written Essays - 250 words

MGMT 436 U5 DB - Research Paper Example Which of the 4 change projects should the consulting group suggest helping the company design and develop? Which function can the company OD do better (as primary lead consultant) than an external group? The consulting group should suggest a change project which would assist the company in generating the most profits within the minimum cost. As such, the company OD, who has access to pertinent information, which is privy to an external group, would enable them to function better. Generate ideas about how you can move toward making the leadership team more independent. What would you have to see happen or what evidence would you look for to see that you can terminate your relationship with the team without any damage being done? To make the leadership team become more independent, the following suggestions are proposed: (1) assign a team leader who would be tasked to solicit ideas, comments, suggestions to undertake a particular project or task; (2) delegate roles and responsibilities of members; (3) monitor progress of the project regularly; and (4) only elevate crucial issues that cannot be resolved by the team to authorized superiors. As such, when the team is able to operate and perform independently and has been able to consistently deliver the expected outcome or defined goals, then, one could terminate the relationship with the team without any damage being done. Provide your thoughts about with which projects the consulting group should be involved. You know you could help with them all, but what is ethical? How much money and time can you, as consultants, lose or make based on this decision? What should drive the decision process? The projects that the consulting group should be involved are those that have never been undertaken by any teams within the organization. This means that the project should be new, complex or not within the traditional area of specialization of the organization. It is therefore ethical to

Stem Barks of Bauhinia Acuminata | Analysis

Stem Barks of Bauhinia Acuminata | Analysis Materials and Methods Plant collection The stem barks of Bauhinia acuminata L. were collected from Rajshahi university campus, Bangladesh, in the month of September, 2013. The plant was authenticated by a taxonomist of Department of Botany, University of Rajshahi. A voucher specimen (Voucher No. MN-13) was deposited to the herbarium in the Department of Botany, University of Rajshahi. The stem barks were then washed separately with fresh water to remove dirty materials and were shade dried for several days with occasional sun drying. The dried barks were then ground into coarse powder by grinding machine and the materials were stored in dark at room temperature for future use. Extract preparation The extraction was performed according to method described by Alam el al. (Alam et al., 2002). About 400 gm of dried powdered stem bark were taken in an amber colored reagent bottle (2.5-liter capacity) and the materials were soaked in 2.0 liter of 100% methanol. The bottle with its contents were sealed and kept for a period of about 7 days with occasional shaking and stirring. The whole mixture was then filtered through cotton and then through Whatman No.1 filters paper and were concentrated with a rotary evaporator (Bibby Sterlin Ltd, UK) under reduced pressure at 45ÂÂ °C temperature to afford crude extract of the bark. The crude extract was mixed with 90% methanol in water to obtain a slurry of satisfactory volume of 100ml. The slurry was taken in a separating funnel and added equal amount of different partitioning solvent sequentially as like n-hexane, chloroform, ethyl acetate and finally water. The funnel was shaken vigorously and allowed to stand for a few minutes for sep aration of the compounds according to their partition co-efficient and thus extracts were prepared for the experiment purpose. The process was repeated three times. At last, the different fractionated parts were evaporated using rotary evaporator at 400C to obtain n-hexane fraction (NHF, 1.12 gm), chloroform fraction (CHF, 1.33 gm), ethyl acetate fraction (EAF, 2.27 gm) and aqueous fraction (AQF, 8.86 gm) respectively. Chemicals 1,1-diphenyl-2-picrylhydrazyl (DPPH), potassium ferricyanide, catechin (CA), ferrous ammonium sulphate, butylated hydroxytoluene (BHT), gallic acid (GA), ascorbic acid (AA), AlCl3, trichloro acetic acid (TCA), sodium phosphate, sodium nitrate, ammonium molybdate, 2-deoxy ribose, sodium hydroxide, EDTA and FeCl3 were purchased from Sigma Chemical Co. (St. Louis, MO, USA); potassium acetate, phosphate buffer, thiobarbituric acid(TBA),ÂÂ   HCl, H2SO4, H2O2were purchased from Sigma-Aldrich, vinblastine sulphate (VBS) from Cipla India, folin-ciocalteuss phenol reagent and sodium carbonate were obtained from Merck (Dam-stadt, Germany). Determination of total phenolics Total phenolic contents in the extracts were determined by the Folin-Ciocalteu method described by Singleton et al. (Slinkard Singleton, 1977). 40 ÂÂ µl of the extract/fractions (250ÂÂ µg/ml) were taken in test tubes and to each 3.16 ml of water was added to make up the volume 3.2ml. 200 ÂÂ µl of folin-Ciocalteu (Undiluted) reagent solution was added into the test tubes and kept for 5-8min. 600 ÂÂ µl of sodium carbonate (20%) solution was added into the test tubes and shake to mix. The test tubes were incubated for 2 hours at 20ËÅ ¡C to complete the reaction. Then the absorbance of the solution was measured at 765 nm using a spectrophotometer (Shimadzu, USA) against blank solution. A typical blank solution contains all reagents except plant extract or standard solution. Standard Gallic acid solutions (50-250ÃŽÂ ¼g /ml) concentrations were also treated as above. The total content of phenolic compounds in plant methanol extract and in different fractions wa s expressed as Gallic acid equivalent (GAE)/gm of dry extract in respect to standard gallic acid curve equation (y = 0.0008x 0.005, RÂÂ ² = 0.975). Determination of total flavonoids Total flavonoids were estimated using aluminum chloride colorimetric assay described by Zhishen et al. (Zhishen, Mengcheng, Jianming, 1999). To 0.5 ml of samples/standard, 150 ÂÂ µl of 5% sodium nitrate and 2.5 ml of distilled water were added. After 5 min, 0.3 ml of 10% AlCl3 was added. At 6 min, 1 ml of 0.001M NaOH and 0.55 ml distilled water was added to the mixture and left at RT for 15 min.ÂÂ   Absorbance of the mixtures was measured at 510 nm. Total flavonoid contents were expressed in terms of catechin equivalent, CAE /gm of dry extract in respect to standard curve equation (y = 0.0178x+0.0524, RÂÂ ² = 0.9862). Determination of free radical scavenging activity DPPH radical scavenging activity Free radical scavenging ability of the extracts was tested by DPPH radical scavenging assay (DRSA) as described by Braca et al. (Braca et al., 2001). Aliquots of 2.5mL of methanolic solution containing sample at different concentration was mixed with 2.5 ml of 0.008% DPPH solution in methanol. The reaction mixture was vortexed thoroughly and left in the dark at room temperature for 30 minutes. The absorbance of the mixture was measured spectrophotometrically at 517 nm. Ascorbic acid was used as reference. Percentage DPPH radical scavenging activity (% DRSA) was calculated by the following equation, % DRSA = (A0-A1/A0) x 100 Where, A0 = Absorbance of control and A1 = Absorbance of sample. IC50 values denote the concentration of sample required to scavenge 50% DPPH free radicals. Hydrogen peroxide scavenging activity Hydrogen peroxide scavenging activity of extract was assessed by the method described by Zhang et al. (Zhang He). Aliquot of 1.0 ml of 0.1mmol/L H2O2 and 1.0 ml of various concentrations of extracts were mixed. Followed by 2 drops of 3% ammonium molybdate, 10 ml of 2M H2SO4 and 7.0 ml of 1.8 mol/L KI. The mixed solution was titrated with 5.09mmol/L Na2S2O3 until yellow color disappeared. The extent of scavenging of hydrogen peroxide was calculated as: % scavenging of hydrogen peroxide = [(V0-V1) / V0] ÃÆ'- 100 Where, V0 = Volume of Na2S2O3 solution used to titrate the control sample in the presence of hydrogen peroxide (without sample), V1 = Volume of Na2S2O3 solution used in the presence of samples. Hydroxyl radical scavenging activity Hydroxyl radical scavenging activity (HRSA) of the extracts was determined by the method of Halliwell et al. (Halliwell, Gutteridge, Aruoma, 1987) with a slight modification. 100 ÂÂ µl of various concentrations of extracts were mixed with 100 ÂÂ µl of hydrogen peroxide (10mmol/L). To this 200 ÂÂ µl premixed FeCl3 (100mmol/L) and EDTA (100mmol/L) solution (1:1;v/v) was added. Followed by addition of 500 ÂÂ µl of 2.8mmol/L 2-deoxyribose in phosphate buffer (PH7.4) and finally the reaction was triggered by adding 100 ÂÂ µl ascorbate (300mmol/L).ÂÂ   Then the reaction mixture was incubated at 37.5ËÅ ¡C for 1 hour. To the above reaction mixture 2 ml of TCA (2.8% w/v aqueous solution) and 2 ml of TBA (1% w/v aqueous solution) was added. The final reaction mixture was heated for 15min in boiling water bath, cooled and absorbance was taken at 532nm using a spectrophotometer. The hydroxyl radical scavenging capacity was evaluated with the inhibition percentage of 2-deoxyribose oxidation on hydroxyl radicals. The percentage of hydroxyl radical scavenging (%HRSA) activity was calculated according to the following formula: % HRSA = [A0 (A1-A2] ÃÆ'-100/A0 where A0 is the absorbance of the control without a sample. A1 is the absorbance after adding the sample and 2-deoxyribose. A2 is the absorbance of the sample without 2-deoxyribose. REFERENCES Alam, A., Rahman, M., Baki, M., Rashid, M., Bhuyan, M., Sadik, G. (2002). Antidiarrhoeal principle of Achyranthes ferruginea Roxb. and their cytotoxicity. Ban Pharm J, 12, 1-4. Braca, A., De Tommasi, N., Di Bari, L., Pizza, C., Politi, M., Morelli, I. (2001). Antioxidant Principles from Bauhinia tarapotensis. Journal of Natural Products, 64(7), 892-895. doi:10.1021/np0100845 Halliwell, B., Gutteridge, J. M., Aruoma, O. I. (1987). The deoxyribose method: a simple test-tube assay for determination of rate constants for reactions of hydroxyl radicals. Anal Biochem, 165(1), 215-219. Slinkard, K., Singleton, V. L. (1977). Total Phenol Analysis: Automation and Comparison with Manual Methods. American Journal of Enology and Viticulture, 28(1), 49-55. Zhang, X., He, F. Science Press; Beijing, China: 2000. Principle of Chemical Analysis, 275-276. Zhishen, J., Mengcheng, T., Jianming, W. (1999). The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food chemistry, 64(4), 555-559.

Indifference to War in Remarque’s All Quiet on the Western Front Essay

Indifference to War in Remarque’s All Quiet on the Western Front In Remarque’s All Quiet on the Western Front, characters such as Paul and his friends become indifferent to shocking elements of war through constant exposure to them. For example, the characters are unconcerned about the dangers of the front because they are accustomed to being on the front. In another instance, Paul’s friends show no emotions when they witness snipers killing enemy soldiers. Also, Kat finds the unusual effects of mortar shells amusing. These examples prove that through war, characters of the book have become indifferent to things that they would normally find shocking. Many characters on the front are indifferent to the dangers of the front. They are not concerned about near death e...

Visual Merchandising

Visual Merchandising: Visual Merchandising is very important because the first impression of the product or store on the customer is by visualizing. If the impression is positive then customers attract to the store. A store must have the inviting appearance to the customers. Objectives of Visual Merchandising: Objective of visual merchandise is to attract the customers to your business in order to sell the merchandise. The main objective is to make the customers feel comfortable and eager to buy. Essential of Visual Merchandising: * Interior Floor  Design  and Display. * Space and Signage. * Window Display. Tools Use for Visual Merchandising: Audio-Visual Displays. * Decoration and Props. * Signage and Graphics. The presentation in visual merchandising falls into two categories mainly: 1. Exterior Presentations. 2. Interior Presentations. Exterior Presentations: The outlook of a store is a major determinant for a customer. Good exterior presentation attracts attention, creates in terest and invites the customer into business. It involves exterior signs, banners and window display. Exterior Signs: A store sign is its â€Å"signature† which tells the customers that what type of the business and what it sells. In less than 10sec the sign must attract attention.Banners: Banners are used to sales promotion. It should be very colorful and eye catching. Window Display: Some products should be placed on a store’s window. Window display should attract attention, create interest and invite people into the store to purchase goods. New displays indicate new up-to-date merchandise is available. Interior Presentations: Another way of the merchandising is through interior display that effectively show merchandise to the customers. The purpose of doing this is to develop interest for the merchandise. It involves color theme and images, lighting, props and fixtures. Researchers found that 64. % of all purchase decision was made inside a store. Three goals of st ore are- 1. Motivate the customers to spend money 2. Protect the image of the store 3. Keep expenses to minimum Color and Lighting: Color in a display can catch eye and make people pause and look. The overall color combination can affect the atmosphere of a store. Lighting is essential in calling attention to merchandise in a display. Customer’s eye is drawn automatically to the brightest area. Props and Fixtures: A display prop is not for sale, it is just used with a product in a display to clarify the function of the product being sold.Merchandise and Fixture Display Recommendations: Goods can be effectively displayed on a variety of fixtures such as tables, cubes, racks and other display cases. Movable shelves from all sides used in self-service retail stores to display merchandise. They can be lined up in stores as grocery or hardware stores. Errors Commonly Occurring in Display: * Too much merchandise * Too little merchandise * Too many props * Poorly selected props * Di splay changed to seldom * Limited or no display budget * Lack of attention to detail

Ap Gov Unit 3 - 1006 Words

What important purposes are served by the right to amend the Constitution guaranteed by Article V? Evaluate James Madison’s claim in Federalist 43 that the Constitution â€Å"guards equally against the extreme facility which would render the Constitution too mutable, and that extreme difficulty which might perpetuate its discovered faults.† Some critics of the amending process contend that amendments, once proposed, should be submitted to popular vote, bypassing state legislatures. Do you agree or disagree? Why? P1. According to professor Douglas Linder, the delegates assembled in Philadelphia were under no illusions that the constitutional scheme they were struggling to establish was perfect for present circumstances, much less perfect†¦show more content†¦According to John Locke, the government derives its power from the people. Choosing to bypass state legislatures and resorting to state conventions forces people to participate in government and have a direct say in laws that affect them. The creation of the constitution is intended to uphold the concept behind limited government and promote civic virtue. P.7 With the end of the Civil War and the 14th Amendment’s creation of a national citizenship, the Court has found that most of the rights recognized in the Bill of Rights apply to state constitutions through the due process clause. Beginning in the 1920s and most recently in 2011 the Court has used this amendment to amend state constitutions through a process that Ma dison most likely could not have envisioned in 1787. P.8 Since 1789, members of Congress have proposed over 10,000 amendments. Only 33 have passed through Congress, and of those only 27 have been ratified by the states. 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